21 December 2009
2.8 mill for research in Type 2 Diabetes
Jonas Thue Treebak has received 3 years postdoc for the project "Involvement of TBC1D1 and TBC1D4 in glucose and fatty acid metabolism".
Type 2 Diabetes (T2D) is one of the most rapidly growing diseases worldwide and are now being diagnosed in middle-aged and as well as young people. T2D is characterized by peripheral insulin resistance, primarily in skeletal muscle and adipose tissue, and hyperlipidaemia, and results from obesity and inactivity.
Physical exercise can reduce or even reverse impaired insulin sensitivity by increasing the sensitivity towards insulin and thus contribute to the removal of glucose from the bloodstream without the involvement of insulin.
Even though we have known the beneficial effects of exercise for decades we still do not completely know the signaling pathways in skeletal muscle which are important for glucose and fatty acid uptake in response to muscle contraction and insulin stimulation.
Therefore, we need treatment strategies for people with impaired insulin sensitivity that are based on results obtained from proper scientific experiments.
Jonas Thue Treebak, mobil: +45 30 20 34 07